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Dose-dependent Inhibition of Tobacco Smoke Carcinogen-induced Lung Tumorigenesis in A/J Mice by Indole-3-carbinol

Recently, we reported inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) plus benzo[a]pyrene (BaP)-induced lung tumorigenesis in A/J mice by indole-3-carbinol I3C (112 μmol/g diet) administered beginning at 50% in the carcinogen treatment phase. In this study, we examined the dose-de...

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Detalhes bibliográficos
Main Authors: Kassie, Fekadu, Matise, Ilze, Negia, Mesfin, Upadhyaya, Pramod, Hecht, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874887/
https://ncbi.nlm.nih.gov/pubmed/19139007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0064
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