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Metformin prevents tobacco carcinogen-induced lung tumorigenesis

Activation of the mTOR pathway is an important and early event in tobacco carcinogen-induced lung tumorigenesis, and therapies that target mTOR could be effective in the prevention or treatment of lung cancer. The biguanide metformin, which is widely prescribed for the treatment of type II diabetes,...

詳細記述

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書誌詳細
主要な著者: Memmott, Regan M., Mercado, Jose R., Maier, Colleen R., Kawabata, Shigeru, Fox, Stephen D., Dennis, Phillip A.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192328/
https://ncbi.nlm.nih.gov/pubmed/20810672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0055
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