Something lost — something gained: the ASCI begins its second century

Por Sawyers, Charles L.
Publicado em 2008

Translational research: are we on the right track?

Por Sawyers, Charles L.
Publicado em 2008

The 2011 Gordon Wilson Lecture: Overcoming Resistance to Targeted Cancer Drugs

Por Sawyers, Charles L.
Publicado em 2012

Coordinate Transcriptional Regulation by ERG and Androgen Receptor in Fusion-Positive Prostate Cancers

Por Chen, Yu, Sawyers, Charles L.
Publicado em 2010

Converting Cancer Therapies into Cures: Lessons from Infectious Diseases

Por Glickman, Michael S., Sawyers, Charles L.
Publicado em 2012

Therapeutic kinase inhibitors

Por Mellinghoff, Ingo K., Sawyers, Charles L.
Publicado em 2012

NF-κB Activates Prostate-Specific Antigen Expression and Is Upregulated in Androgen-Independent Prostate Cancer

Por Chen, Charlie D., Sawyers, Charles L.
Publicado em 2002

“N of 1” case reports in the era of whole-genome sequencing

Por Brannon, A. Rose, Sawyers, Charles L.
Publicado em 2013

Treating Imatinib-Resistant Leukemia: The Next Generation Targeted Therapies

Por Burgess, Michael R., Sawyers, Charles L.
Publicado no ScientificWorldJournal (2006)

Strategies to Identify and Target Cells of Origin in Prostate Cancer

Por Karthaus, Wouter R, Sawyers, Charles L
Publicado no J Natl Cancer Inst (2018)

Challenges in validating candidate therapeutic targets in cancer

Por Settleman, Jeffrey, Sawyers, Charles L, Hunter, Tony
Publicado no eLife (2018)

Targeting the androgen receptor pathway in prostate cancer

Por Chen, Yu, Sawyers, Charles L., Scher, Howard I.
Publicado em 2008

Structural Requirements for Function of the Crkl Adapter Protein in Fibroblasts and Hematopoietic Cells

Por Senechal, Kristen, Heaney, Conor, Druker, Brian, Sawyers, Charles L.
Publicado em 1998

Emerging Mechanisms of Resistance to Androgen Receptor Inhibitors in Prostate Cancer

Por Watson, Philip A., Arora, Vivek K., Sawyers, Charles L.
Publicado no Nat Rev Cancer (2015)

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses

Por Pappas, Kyrie J., Choi, Danielle, Sawyers, Charles L., Karthaus, Wouter R.
Publicado no J Vis Exp (2019)

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

Por Wu, Xinyi, Senechal, Kristen, Neshat, Mehran S., Whang, Young E., Sawyers, Charles L.
Publicado em 1998

Visualization of the Interstitial Cells of Cajal (ICC) Network in Mice

Por Chen, Yu, Shamu, Tambudzai, Chen, Hui, Besmer, Peter, Sawyers, Charles L., Chi, Ping
Publicado em 2011

Fitness Conferred by BCR-ABL Kinase Domain Mutations Determines the Risk of Pre-Existing Resistance in Chronic Myeloid Leukemia

Por Leder, Kevin, Foo, Jasmine, Skaggs, Brian, Gorre, Mercedes, Sawyers, Charles L., Michor, Franziska
Publicado em 2011

Mitogen-Activated Protein Kinase Kinase Kinase 1 Activates Androgen Receptor-Dependent Transcription and Apoptosis in Prostate Cancer

Por Abreu-Martin, Maria T., Chari, Ajai, Palladino, Andrew A., Craft, Noah A., Sawyers, Charles L.
Publicado em 1999

The Survival Function of the Bcr-Abl Oncogene Is Mediated by Bad-Dependent and -Independent Pathways: Roles for Phosphatidylinositol 3-Kinase and Raf

Por Neshat, Mehran S., Raitano, Arthur B., Wang, Hong-Gang, Reed, John C., Sawyers, Charles L.
Publicado em 2000