The Survival Function of the Bcr-Abl Oncogene Is Mediated by Bad-Dependent and -Independent Pathways: Roles for Phosphatidylinositol 3-Kinase and Raf

The Bcr-Abl tyrosine kinase constitutively activates cytokine signal transduction pathways that stimulate growth and prevent apoptosis in hematopoietic cells. The antiapoptotic action of interleukin-3 (IL-3) has been linked to a signaling pathway which inactivates the proapoptotic protein Bad by pho...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Neshat, Mehran S., Raitano, Arthur B., Wang, Hong-Gang, Reed, John C., Sawyers, Charles L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.4.1179-1186.2000
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