The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation.
Proliferation of normal cells in a multicellular organism requires not only growth factors but also the proper attachment to the extracellular matrix. A hallmark of neoplastic transformation is the loss of anchorage dependence which usually accompanies the loss of growth factor requirement. The Bcr-...
Na minha lista:
| Publicado no: | Mol Cell Biol |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1995
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1286 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|