Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors

Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role of PSMA has not been explored, and its role in prostate cancer remained elusi...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Kaittanis, Charalambos, Andreou, Chrysafis, Hieronymus, Haley, Mao, Ninghui, Foss, Catherine A., Eiber, Matthias, Weirich, Gregor, Panchal, Palak, Gopalan, Anuradha, Zurita, Juan, Achilefu, Samuel, Chiosis, Gabriela, Ponomarev, Vladimir, Schwaiger, Markus, Carver, Brett S., Pomper, Martin G., Grimm, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748857/
https://ncbi.nlm.nih.gov/pubmed/29141866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171052
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