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Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors

Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role of PSMA has not been explored, and its role in prostate cancer remained elusi...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Kaittanis, Charalambos, Andreou, Chrysafis, Hieronymus, Haley, Mao, Ninghui, Foss, Catherine A., Eiber, Matthias, Weirich, Gregor, Panchal, Palak, Gopalan, Anuradha, Zurita, Juan, Achilefu, Samuel, Chiosis, Gabriela, Ponomarev, Vladimir, Schwaiger, Markus, Carver, Brett S., Pomper, Martin G., Grimm, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748857/
https://ncbi.nlm.nih.gov/pubmed/29141866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171052
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