Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors

Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role of PSMA has not been explored, and its role in prostate cancer remained elusi...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Kaittanis, Charalambos, Andreou, Chrysafis, Hieronymus, Haley, Mao, Ninghui, Foss, Catherine A., Eiber, Matthias, Weirich, Gregor, Panchal, Palak, Gopalan, Anuradha, Zurita, Juan, Achilefu, Samuel, Chiosis, Gabriela, Ponomarev, Vladimir, Schwaiger, Markus, Carver, Brett S., Pomper, Martin G., Grimm, Jan
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748857/
https://ncbi.nlm.nih.gov/pubmed/29141866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171052
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