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Synthesis of 4-aminoquinoline–pyrimidine hybrids as potent antimalarials and their mode of action studies

One of the most viable options to tackle the growing resistance to the antimalarial drugs such as artemisinin is to resort to synthetic drugs. The multi-target strategy involving the use of hybrid drugs has shown promise. In line with this, new hybrids of quinoline with pyrimidine have been synthesi...

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Dettagli Bibliografici
Pubblicato in:Eur J Med Chem
Autori principali: Singh, Kamaljit, Kaur, Hardeep, Chibale, Kelly, Balzarini, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Masson SAS. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115683/
https://ncbi.nlm.nih.gov/pubmed/23811093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.05.046
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