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Synthesis of 4-aminoquinoline–pyrimidine hybrids as potent antimalarials and their mode of action studies

One of the most viable options to tackle the growing resistance to the antimalarial drugs such as artemisinin is to resort to synthetic drugs. The multi-target strategy involving the use of hybrid drugs has shown promise. In line with this, new hybrids of quinoline with pyrimidine have been synthesi...

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Podrobná bibliografie
Vydáno v:Eur J Med Chem
Hlavní autoři: Singh, Kamaljit, Kaur, Hardeep, Chibale, Kelly, Balzarini, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Masson SAS. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115683/
https://ncbi.nlm.nih.gov/pubmed/23811093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.05.046
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