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Synthesis and Antimalarial Activities of Cyclen 4-Aminoquinoline Analogs
In an attempt to augment the efficacy of 7-chloro 4-aminoquinoline analogs and also to overcome resistance to antimalarial agents, we synthesized three cyclen (1,4,7,10-tetraazacyclododecane) analogs of chloroquine [a bisquinoline derivative, 7-chloro-4-(1,4,7,10-tetraaza-cyclododec-1-yl)-quinoline...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663103/ https://ncbi.nlm.nih.gov/pubmed/19171802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01304-08 |
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