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Synthesis and Antimalarial Activities of Cyclen 4-Aminoquinoline Analogs

In an attempt to augment the efficacy of 7-chloro 4-aminoquinoline analogs and also to overcome resistance to antimalarial agents, we synthesized three cyclen (1,4,7,10-tetraazacyclododecane) analogs of chloroquine [a bisquinoline derivative, 7-chloro-4-(1,4,7,10-tetraaza-cyclododec-1-yl)-quinoline...

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Hlavní autoři: Khan, M. O. Faruk, Levi, Mark S., Tekwani, Babu L., Khan, Shabana I., Kimura, Eiichi, Borne, Ronald F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663103/
https://ncbi.nlm.nih.gov/pubmed/19171802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01304-08
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