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Synthesis of 4-aminoquinoline–pyrimidine hybrids as potent antimalarials and their mode of action studies

One of the most viable options to tackle the growing resistance to the antimalarial drugs such as artemisinin is to resort to synthetic drugs. The multi-target strategy involving the use of hybrid drugs has shown promise. In line with this, new hybrids of quinoline with pyrimidine have been synthesi...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Singh, Kamaljit, Kaur, Hardeep, Chibale, Kelly, Balzarini, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Masson SAS. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115683/
https://ncbi.nlm.nih.gov/pubmed/23811093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2013.05.046
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