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Novel 4-Aminoquinoline Analogs Highly Active against the Blood and Sexual Stages of Plasmodium In Vivo and In Vitro

New drugs to treat malaria must act rapidly and be highly potent against asexual blood stages, well tolerated, and affordable to residents of regions of endemicity. This was the case with chloroquine (CQ), a 4-aminoquinoline drug used for the prevention and treatment of malaria. However, since the 1...

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Detalhes bibliográficos
Main Authors: Sáenz, Fabián E., Mutka, Tina, Udenze, Kenneth, Oduola, Ayoade M. J., Kyle, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421852/
https://ncbi.nlm.nih.gov/pubmed/22710117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01061-12
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