ロード中...
Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
Organophosphate (OP) intoxications from nerve agent and OP pesticide exposures are managed with pyridinium aldoxime–based therapies whose success rates are currently limited. The pyridinium cation hampers uptake of OPs into the central nervous system (CNS). Furthermore, it frequently binds to aromat...
保存先:
| 出版年: | J Biol Chem |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2020
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7105318/ https://ncbi.nlm.nih.gov/pubmed/32019865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012400 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|