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Redox-Annulations of Cyclic Amines with ortho-Cyanomethylbenz-aldehydes
Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with ortho-cyanomethylbenz-aldehydes. These amine α-C–H bond functionalization reactions are promoted by acetic acid. The resulting β-aminonitriles can be converted to the corresponding β-aminoalcohols in diastereoselect...
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| 出版年: | Org Lett |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104785/ https://ncbi.nlm.nih.gov/pubmed/31984752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b04506 |
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