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Redox-Annulations of Cyclic Amines with ortho-Cyanomethylbenz-aldehydes
Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with ortho-cyanomethylbenz-aldehydes. These amine α-C–H bond functionalization reactions are promoted by acetic acid. The resulting β-aminonitriles can be converted to the corresponding β-aminoalcohols in diastereoselect...
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| Gepubliceerd in: | Org Lett |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7104785/ https://ncbi.nlm.nih.gov/pubmed/31984752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b04506 |
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