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Redox-Annulations of Cyclic Amines with 2-(2-Oxoethyl)Malonates

Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-(2-oxoethyl)malonates in the presence of catalytic amounts of benzoic acid. These reactions install a fully saturated 5-membered ring and provide access to structures closely related to the natural products crispi...

詳細記述

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書誌詳細
出版年:Org Lett
主要な著者: Zhu, Zhengbo, Chandak, Hemant S., Seidel, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060407/
https://ncbi.nlm.nih.gov/pubmed/29939750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01642
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