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Redox-Annulations of Cyclic Amines with 2-(2-Oxoethyl)Malonates

Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with 2-(2-oxoethyl)malonates in the presence of catalytic amounts of benzoic acid. These reactions install a fully saturated 5-membered ring and provide access to structures closely related to the natural products crispi...

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Publicado en:Org Lett
Main Authors: Zhu, Zhengbo, Chandak, Hemant S., Seidel, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060407/
https://ncbi.nlm.nih.gov/pubmed/29939750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01642
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