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Traceless Redox-Annulations of Alicyclic Amines

Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with ortho-(nitromethyl)benzaldehyde. Benzoic acid acts as a promoter in these reactions, which involve concurrent amine α-C–H bond and N–H bond functionalization. Subsequent removal of the nitro group provides access to...

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Detalhes bibliográficos
Publicado no:SynOpen
Main Authors: Rickertsen, Dillon R. L., Ma, Longle, Paul, Anirudra, Abboud, Khalil A., Seidel, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318209/
https://ncbi.nlm.nih.gov/pubmed/34327302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1706004
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