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Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway
We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair. In the current study, we confirmed that Dnmt3b ablation in mesenchymal progenitor cells (MPCs) resulted in...
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| Publicado en: | JCI Insight |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098799/ https://ncbi.nlm.nih.gov/pubmed/32051335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131816 |
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