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Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway

We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair. In the current study, we confirmed that Dnmt3b ablation in mesenchymal progenitor cells (MPCs) resulted in...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Ying, Jun, Xu, Taotao, Wang, Cuicui, Jin, Hongting, Tong, Peijian, Guan, Jianjun, Abu-Amer, Yousef, O’Keefe, Regis, Shen, Jie
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098799/
https://ncbi.nlm.nih.gov/pubmed/32051335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131816
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