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Loss of Dnmt3b in Chondrocytes Leads to Delayed Endochondral Ossification and Fracture Repair

Despite advanced understanding of signaling mediated by local and systemic factors, the role of epigenetic factors in the regulation of bone regeneration remains vague. The DNA methyltransferases (Dnmts) Dnmt3a and Dnmt3b have tissue specific expression patterns and create unique methylation signatu...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Wang, Cuicui, Abu-Amer, Yousef, O’Keefe, Regis J, Shen, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809267/
https://ncbi.nlm.nih.gov/pubmed/29024060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3305
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