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Loss of Dnmt3b in Chondrocytes Leads to Delayed Endochondral Ossification and Fracture Repair

Despite advanced understanding of signaling mediated by local and systemic factors, the role of epigenetic factors in the regulation of bone regeneration remains vague. The DNA methyltransferases (Dnmts) Dnmt3a and Dnmt3b have tissue specific expression patterns and create unique methylation signatu...

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Bibliografiska uppgifter
I publikationen:J Bone Miner Res
Huvudupphovsmän: Wang, Cuicui, Abu-Amer, Yousef, O’Keefe, Regis J, Shen, Jie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809267/
https://ncbi.nlm.nih.gov/pubmed/29024060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3305
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