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Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development
DNA methylation is a major mode of epigenetic regulation in the mammalian genome and is essential for embryonic development. The three catalytic DNA methyltransferases (Dnmts), Dnmt1, Dnmt3a, and Dnmt3b, catalyze the methylation of cytosine. Dnmt3b is highly expressed in chondrocytes and global knoc...
Gardado en:
| Publicado en: | J Cell Biochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993586/ https://ncbi.nlm.nih.gov/pubmed/29637597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26775 |
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