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Regulation of Embryonic Endochondral Ossification by Smurf2
Smurf2 is an E3 ubiquitin ligase that targets TGF-β receptor activated Smad2 and Smad3 for the proteasome in primary articular chondrocytes, thus stimulating their hypertrophic differentiation. Comparatively, how Smurf2 functions in growth plate chondrocytes in a developing long bone is an open ques...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2636972/ https://ncbi.nlm.nih.gov/pubmed/18176945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.20563 |
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