Overexpression of Smurf2 Stimulates Endochondral Ossification Through Upregulation of β-Catenin

Ectopic expression of Smurf2 in chondrocytes and perichondrial cells accelerated endochondral ossification by stimulating chondrocyte maturation and osteoblast development through upregulation of β-catenin in Col2a1-Smurf2 embryos. The mechanism underlying Smurf2-mediated morphological changes durin...

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Autores principales: Wu, Qiuqian, Chen, Di, Zuscik, Michael J, O'Keefe, Regis J, Rosier, Randy N
Formato: Artigo
Lenguaje:Inglês
Publicado: Amer Soc Bone & Mineral Res. 2008
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636709/
https://ncbi.nlm.nih.gov/pubmed/18052755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.071115
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