Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

Osteoarthritis (OA) is a degenerative joint disease, and the mechanism of its pathogenesis is poorly understood. Recent human genetic association studies showed that mutations in the Frzb gene predispose patients to OA, suggesting that the Wnt/β-catenin signaling may be the key pathway to the develo...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhu, Mei, Tang, Dezhi, Wu, Qiuqian, Hao, Suyang, Chen, Mo, Xie, Chao, Rosier, Randy N, O'Keefe, Regis J, Zuscik, Michael, Chen, Di
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Amer Soc Bone & Mineral Res. 2009
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640321/
https://ncbi.nlm.nih.gov/pubmed/18767925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080901
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