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NOTCH signaling in skeletal progenitors is critical for fracture repair

Fracture nonunions develop in 10%–20% of patients with fractures, resulting in prolonged disability. Current data suggest that bone union during fracture repair is achieved via proliferation and differentiation of skeletal progenitors within periosteal and soft tissues surrounding bone, while bone m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Wang, Cuicui, Inzana, Jason A., Mirando, Anthony J., Ren, Yinshi, Liu, Zhaoyang, Shen, Jie, O’Keefe, Regis J., Awad, Hani A., Hilton, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811137/
https://ncbi.nlm.nih.gov/pubmed/26950423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80672
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