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Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks

DNA double-stranded breaks (DSBs) are strongly associated with active transcription, and promoter-proximal pausing of RNA polymerase II (Pol II) is a critical step in transcriptional regulation. Mapping the distribution of DSBs along actively expressed genes and identifying the location of DSBs rela...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Singh, Sandeep, Szlachta, Karol, Manukyan, Arkadi, Raimer, Heather M., Dinda, Manikarna, Bekiranov, Stefan, Wang, Yuh-Hwa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086017/
https://ncbi.nlm.nih.gov/pubmed/32029477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011665
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