Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae

Molecular combing and gel electrophoretic studies revealed endogenous nicks with free 3′OH ends at ∼100 kb intervals in the genomic DNA (gDNA) of unperturbed and G1-synchronized Saccharomyces cerevisiae cells. Analysis of the distribution of endogenous nicks by Nick ChIP-chip indicated that these br...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hegedüs, Éva, Kókai, Endre, Nánási, Péter, Imre, László, Halász, László, Jossé, Rozenn, Antunovics, Zsuzsa, Webb, Martin R, El Hage, Aziz, Pommier, Yves, Székvölgyi, Lóránt, Dombrádi, Viktor, Szabó, Gábor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237785/
https://ncbi.nlm.nih.gov/pubmed/30445637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky743
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