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Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks
DNA double-stranded breaks (DSBs) trigger human genome instability, therefore identifying what factors contribute to DSB induction is critical for our understanding of human disease etiology. Using an unbiased, genome-wide approach, we found that genomic regions with the ability to form highly stabl...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337936/ https://ncbi.nlm.nih.gov/pubmed/32501506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa483 |
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