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CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution

BACKGROUND: DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical information concerning the consequences of the damage. Therefore, there has been a rec...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Szlachta, Karol, Raimer, Heather M., Comeau, Laurey D., Wang, Yuh-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950916/
https://ncbi.nlm.nih.gov/pubmed/31914926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-6436-0
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