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DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution
DNA single-strand breaks (SSBs), or “nicks,” are the most common form of DNA damage. Oxidative stress, endogenous enzyme activities, and other processes cause tens of thousands of nicks per cell per day. Accumulation of nicks, caused by high rates of occurrence or defects in repair enzymes, has been...
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| Udgivet i: | Genome Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849381/ https://ncbi.nlm.nih.gov/pubmed/33355294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265223.120 |
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