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DENT-seq for genome-wide strand-specific identification of DNA single-strand break sites with single-nucleotide resolution

DNA single-strand breaks (SSBs), or “nicks,” are the most common form of DNA damage. Oxidative stress, endogenous enzyme activities, and other processes cause tens of thousands of nicks per cell per day. Accumulation of nicks, caused by high rates of occurrence or defects in repair enzymes, has been...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Res
Egile Nagusiak: Elacqua, Joshua J., Ranu, Navpreet, DiIorio, Sarah E., Blainey, Paul C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849381/
https://ncbi.nlm.nih.gov/pubmed/33355294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265223.120
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