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Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks
DNA double-stranded breaks (DSBs) are strongly associated with active transcription, and promoter-proximal pausing of RNA polymerase II (Pol II) is a critical step in transcriptional regulation. Mapping the distribution of DSBs along actively expressed genes and identifying the location of DSBs rela...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7086017/ https://ncbi.nlm.nih.gov/pubmed/32029477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011665 |
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