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NusG Is a Sequence-specific RNA Polymerase Pause Factor That Binds to the Non-template DNA within the Paused Transcription Bubble

NusG, referred to as Spt5 in archaeal and eukaryotic organisms, is the only transcription factor conserved in all three domains of life. This general transcription elongation factor binds to RNA polymerase (RNAP) soon after transcription initiation and dissociation of the RNA polymerase σ factor. Es...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Yakhnin, Alexander V., Murakami, Katsuhiko S., Babitzke, Paul
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777861/
https://ncbi.nlm.nih.gov/pubmed/26742846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704189
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