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NusG Is a Sequence-specific RNA Polymerase Pause Factor That Binds to the Non-template DNA within the Paused Transcription Bubble

NusG, referred to as Spt5 in archaeal and eukaryotic organisms, is the only transcription factor conserved in all three domains of life. This general transcription elongation factor binds to RNA polymerase (RNAP) soon after transcription initiation and dissociation of the RNA polymerase σ factor. Es...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yakhnin, Alexander V., Murakami, Katsuhiko S., Babitzke, Paul
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777861/
https://ncbi.nlm.nih.gov/pubmed/26742846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704189
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