Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

[Image: see text] Tumor targeting using agents with slow pharmacokinetics represents a major challenge in nuclear imaging and targeted radionuclide therapy as they most often result in low imaging contrast and high radiation dose to healthy tissue. To address this challenge, we developed a polymer-b...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:ACS Nano
Main Authors: Stéen, E. Johanna L., Jørgensen, Jesper T., Johann, Kerstin, Nørregaard, Kamilla, Sohr, Barbara, Svatunek, Dennis, Birke, Alexander, Shalgunov, Vladimir, Edem, Patricia E., Rossin, Raffaella, Seidl, Christine, Schmid, Friederike, Robillard, Marc S., Kristensen, Jesper L., Mikula, Hannes, Barz, Matthias, Kjær, Andreas, Herth, Matthias M.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2019
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075664/
https://ncbi.nlm.nih.gov/pubmed/31820928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b06905
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares