Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging

BACKGROUND: Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied in clinical pretargeting studies; unfortunately,...

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發表在:EJNMMI Res
Main Authors: Edem, Patricia E., Sinnes, Jean-Philippe, Pektor, Stefanie, Bausbacher, Nicole, Rossin, Raffaella, Yazdani, Abdolreza, Miederer, Matthias, Kjær, Andreas, Valliant, John F., Robillard, Marc S., Rösch, Frank, Herth, Matthias M.
格式: Artigo
語言:Inglês
出版: Springer Berlin Heidelberg 2019
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538705/
https://ncbi.nlm.nih.gov/pubmed/31140047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-019-0520-y
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