A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels–Alder Click Chemistry

The specificity of antibodies have made immunoconjugates promising vectors for the delivery of radioisotopes to cancer cells; however, their long pharmacologic half-lives necessitate the use of radioisotopes with long physical halsives, a combination that leads to high radiation doses to patients. T...

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Bibliographic Details
Main Authors: Zeglis, Brian M., Sevak, Kuntal K., Reiner, Thomas, Mohindra, Priya, Carlin, Sean D., Zanzonico, Pat, Weissleder, Ralph, Lewis, Jason S.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151562/
https://ncbi.nlm.nih.gov/pubmed/23708196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.115840
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