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Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging

Due to their exquisite affinity and specificity, antibodies have become extremely promising vectors for the delivery of radioisotopes to cancer cells for PET imaging. However, the necessity of labeling antibodies with radionuclides with long physical half-lives often results in high background radia...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Reiner, Thomas, Lewis, Jason S., Zeglis, Brian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354619/
https://ncbi.nlm.nih.gov/pubmed/25742199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52335
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