(18)F-Based Pretargeted PET Imaging Based on Bioorthogonal Diels–Alder Click Chemistry

[Image: see text] A first-of-its-kind (18)F pretargeted PET imaging approach based on the bioorthogonal inverse electron demand Diels–Alder (IEDDA) reaction between tetrazine (Tz) and trans-cyclooctene (TCO) is presented. As proof-of-principle, a TCO-bearing immunoconjugate of the anti-CA19.9 antibo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Meyer, Jan-Philip, Houghton, Jacob L., Kozlowski, Paul, Abdel-Atti, Dalya, Reiner, Thomas, Pillarsetty, Naga Vara Kishore, Scholz, Wolfgang W., Zeglis, Brian M., Lewis, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759614/
https://ncbi.nlm.nih.gov/pubmed/26479967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00504
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados