Evaluation of a (68)Ga-Labeled DOTA-Tetrazine as a PET Alternative to (111)In-SPECT Pretargeted Imaging

The bioorthogonal reaction between a tetrazine and strained trans-cyclooctene (TCO) has garnered success in pretargeted imaging. This reaction was first validated in nuclear imaging using an (111)In-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-linked bispyridyl tetrazine (...

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Publicado no:Molecules
Main Authors: Edem, Patricia E., Jørgensen, Jesper T., Nørregaard, Kamilla, Rossin, Rafaella, Yazdani, Abdolreza, Valliant, John F., Robillard, Marc, Herth, Matthias M., Kjaer, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036891/
https://ncbi.nlm.nih.gov/pubmed/31979070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030463
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