تحميل...
The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme
Alzheimer’s disease (AD) is the most common neurodegenerative disease resulting in dementia. It is characterized pathologically by extracellular amyloid plaques composed mainly of deposited Aβ42 and intracellular neurofibrillary tangles formed by hyperphosphorylated tau protein. Recent clinical tria...
محفوظ في:
| الحاوية / القاعدة: | ACS Chem Neurosci |
|---|---|
| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2018
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7074877/ https://ncbi.nlm.nih.gov/pubmed/30067897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00305 |
| الوسوم: |
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