Structural Insights into Ankyrin Repeat-Containing Proteins and Their Influence in Ubiquitylation

অনুযায়ী Kane, Emma I., Spratt, Donald E.
প্রকাশিত Int J Mol Sci (2021)

Structure of the HHARI Catalytic Domain Shows Glimpses of a HECT E3 Ligase

অনুযায়ী Spratt, Donald E., Mercier, Pascal, Shaw, Gary S.
প্রকাশিত 2013

RBR E3 ubiquitin ligases: new structures, new insights, new questions

অনুযায়ী Spratt, Donald E., Walden, Helen, Shaw, Gary S.
প্রকাশিত 2014

(1)H, (13)C, and (15)N resonance assignments of the C-terminal lobe of the human HECT E3 ubiquitin ligase ITCH

অনুযায়ী Beasley, Steven A., Bardhi, Roela, Spratt, Donald E.
প্রকাশিত Biomol NMR Assign (2018)

Exploring the Roles of HERC2 and the NEDD4L HECT E3 Ubiquitin Ligase Subfamily in p53 Signaling and the DNA Damage Response

অনুযায়ী Mathieu, Nicholas A., Levin, Rafael H., Spratt, Donald E.
প্রকাশিত Front Oncol (2021)

HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response

অনুযায়ী Mathieu, Nicholas A., Paparisto, Ermela, Barr, Stephen D., Spratt, Donald E.
প্রকাশিত Viruses (2021)

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase

অনুযায়ী Spratt, Donald E., Wu, Kenneth, Kovacev, Jordan, Pan, Zhen-Qiang, Shaw, Gary S.
প্রকাশিত 2012

HECT E3 ubiquitin ligases – emerging insights into their biological roles and disease relevance

অনুযায়ী Wang, Yaya, Argiles-Castillo, Diana, Kane, Emma I., Zhou, Anning, Spratt, Donald E.
প্রকাশিত J Cell Sci (2020)

Resveratrol Sustains Insulin-Degrading Enzyme Activity toward Aβ42

অনুযায়ী Krasinski, Claire A., Ivancic, Valerie A., Zheng, Qiuchen, Spratt, Donald E., Lazo, Noel D.
প্রকাশিত ACS Omega (2018)

The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme...

অনুযায়ী Krasinski, Claire A., Zheng, Qiuchen, Ivancic, Valerie A., Spratt, Donald E., Lazo, Noel D.
প্রকাশিত ACS Chem Neurosci (2018)

An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity

অনুযায়ী Beasley, Steven A., Kellum, Chloe E., Orlomoski, Rachel J., Idrizi, Feston, Spratt, Donald E.
প্রকাশিত PLoS One (2020)

Enzyme kinetics from circular dichroism of insulin reveals mechanistic insights into the regulation of insulin-degrading enzyme

অনুযায়ী Ivancic, Valerie A., Krasinski, Claire A., Zheng, Qiuchen, Meservier, Rebecca J., Spratt, Donald E., Lazo, Noel D.
প্রকাশিত Biosci Rep (2018)

Rapid and Efficient Purification of Drosophila Homeodomain Transcription Factors for Biophysical Characterization

অনুযায়ী Orlomoski, Rachel, Bogle, Aaron, Loss, Jeanmarie, Simons, Rylee, Dresch, Jacqueline M., Drewell, Robert A., Spratt, Donald E.
প্রকাশিত Protein Expr Purif (2019)

Crystal structure of the catalytic C‐lobe of the HECT‐type ubiquitin ligase E6AP

অনুযায়ী Ries, Lena K., Liess, Anna K. L., Feiler, Christian G., Spratt, Donald E., Lowe, Edward D., Lorenz, Sonja
প্রকাশিত Protein Sci (2020)

A SnapShot of Ubiquitin Chain Elongation: LYSINE 48-TETRA-UBIQUITIN SLOWS DOWN UBIQUITINATION

অনুযায়ী Kovacev, Jordan, Wu, Kenneth, Spratt, Donald E., Chong, Robert A., Lee, Chan, Nayak, Jaladhi, Shaw, Gary S., Pan, Zhen-Qiang
প্রকাশিত 2014

Intraprotein Electron Transfer in Inducible Nitric Oxide Synthase Holoenzyme

অনুযায়ী Feng, Changjian, Dupont, Andrea L., Nahm, Nickolas J., Spratt, Donald E., Hazzard, James T., Weinberg, J. Brice, Guillemette, J. Guy, Tollin, Gordon, Ghosh, Dipak K.
প্রকাশিত 2008

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease

অনুযায়ী Spratt, Donald E., Julio Martinez-Torres, R, Noh, Yeong J., Mercier, Pascal, Manczyk, Noah, Barber, Kathryn R., Aguirre, Jacob D., Burchell, Lynn, Purkiss, Andrew, Walden, Helen, Shaw, Gary S.
প্রকাশিত 2013

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

অনুযায়ী Kumar, Atul, Aguirre, Jacob D, Condos, Tara EC, Martinez-Torres, R Julio, Chaugule, Viduth K, Toth, Rachel, Sundaramoorthy, Ramasubramanian, Mercier, Pascal, Knebel, Axel, Spratt, Donald E, Barber, Kathryn R, Shaw, Gary S, Walden, Helen
প্রকাশিত EMBO J (2015)

Suramin inhibits cullin-RING E3 ubiquitin ligases

অনুযায়ী Wu, Kenneth, Chong, Robert A., Yu, Qing, Bai, Jin, Spratt, Donald E., Ching, Kevin, Lee, Chan, Miao, Haibin, Tappin, Inger, Hurwitz, Jerard, Zheng, Ning, Shaw, Gary S., Sun, Yi, Felsenfeld, Dan P., Sanchez, Roberto, Zheng, Jun-nian, Pan, Zhen-Qiang
প্রকাশিত Proc Natl Acad Sci U S A (2016)

Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

অনুযায়ী Chong, Robert A., Wu, Kenneth, Spratt, Donald E., Yang, Yingying, Lee, Chan, Nayak, Jaladhi, Xu, Ming, Elkholi, Rana, Tappin, Inger, Li, Jessica, Hurwitz, Jerard, Brown, Brian D., Chipuk, Jerry Edward, Chen, Zhijian J., Sanchez, Roberto, Shaw, Gary S., Huang, Lan, Pan, Zhen-Qiang
প্রকাশিত 2014