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Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase
RING E3 ligases are proteins that must selectively recruit an E2-conjugating enzyme and facilitate ubiquitin transfer to a substrate. It is not clear how a RING E3 ligase differentiates a naked E2 enzyme from the E2∼ubiquitin-conjugated form or how this is altered upon ubiquitin transfer. RING-box p...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366790/ https://ncbi.nlm.nih.gov/pubmed/22433864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353748 |
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