Suramin inhibits cullin-RING E3 ubiquitin ligases

Cullin-RING E3 ubiquitin ligases (CRL) control a myriad of biological processes by directing numerous protein substrates for proteasomal degradation. Key to CRL activity is the recruitment of the E2 ubiquitin-conjugating enzyme Cdc34 through electrostatic interactions between E3′s cullin conserved b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Kenneth, Chong, Robert A., Yu, Qing, Bai, Jin, Spratt, Donald E., Ching, Kevin, Lee, Chan, Miao, Haibin, Tappin, Inger, Hurwitz, Jerard, Zheng, Ning, Shaw, Gary S., Sun, Yi, Felsenfeld, Dan P., Sanchez, Roberto, Zheng, Jun-nian, Pan, Zhen-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833235/
https://ncbi.nlm.nih.gov/pubmed/27001857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601089113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados