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Cullin-Ring ubiquitin ligases in kidney health and disease

1. PURPOSE OF REVIEW: Members of the Cullin family act as scaffolds in E3 ubiquitin ligases and play a central role in mediating protein degradation. Interactions with many different substrate-binding adaptors permit Cullin-containing E3 ligases to participate in diverse cellular functions. In the k...

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Vydáno v:Curr Opin Nephrol Hypertens
Hlavní autoři: Cornelius, Ryan J., Ferdaus, Mohammed Z., Nelson, Jonathan W., McCormick, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686897/
https://ncbi.nlm.nih.gov/pubmed/31313673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000527
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