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Structural assembly of cullin-RING ubiquitin ligase complexes
The cullin-RING ubiquitin ligases (CRL) are the largest family of multi-subunit E3 ligases in eukaryotes, which ubiquitinate protein substrates in numerous cellular pathways. CRLs share a common arched scaffold and a RING domain catalytic subunit, but use different adaptors and substrate receptors t...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070871/ https://ncbi.nlm.nih.gov/pubmed/20880695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2010.08.010 |
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