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Building and remodelling Cullin–RING E3 ubiquitin ligases

Cullin–RING E3 ubiquitin ligases (CRLs) control a plethora of biological pathways through targeted ubiquitylation of signalling proteins. These modular assemblies use substrate receptor modules to recruit specific targets. Recent efforts have focused on understanding the mechanisms that control the...

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Bibliografiska uppgifter
Huvudupphovsmän: Lydeard, John R, Schulman, Brenda A, Harper, J Wade
Materialtyp: Artigo
Språk:Inglês
Publicerad: European Molecular Biology Organization 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849489/
https://ncbi.nlm.nih.gov/pubmed/24232186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.173
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