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Building and remodelling Cullin–RING E3 ubiquitin ligases

Cullin–RING E3 ubiquitin ligases (CRLs) control a plethora of biological pathways through targeted ubiquitylation of signalling proteins. These modular assemblies use substrate receptor modules to recruit specific targets. Recent efforts have focused on understanding the mechanisms that control the...

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Detalhes bibliográficos
Main Authors: Lydeard, John R, Schulman, Brenda A, Harper, J Wade
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849489/
https://ncbi.nlm.nih.gov/pubmed/24232186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.173
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